Acuity is not futility: reconsidering temporary mechanical circulatory support in LVAD candidates with right ventricular dysfunction
Study addressing a common clinical dilemma: in a candidate for a left ventricular assist device who also has right ventricular dysfunction, does the need for temporary mechanical circulatory support before implantation merely identify a sicker but potentially recoverable patient, or does it independently affect long-term prognosis?
Is coronary artery bypass grafting still the best strategy? Final 10-year results of the NOBLE trial in unprotected left main coronary artery disease
Prospective, multicentre, randomised clinical trial comparing the long-term outcomes of percutaneous coronary intervention (PCI) with second-generation drug-eluting stents versus coronary artery bypass grafting (CABG) in patients with significant unprotected left main coronary artery stenosis, with long-term all-cause mortality as the primary outcome.
Perceval® prostheses and sex: similar outcomes, but are they truly equivalent? A critical appraisal from the largest published single-center experience
Prospective multicenter registry and meta-regression assessing outcomes after Perceval Plus® implantation according to sex. The findings support comparable early safety in men and women, although several limitations preclude concluding true equivalence.
Trends in aortic valve replacement among patients aged 65 years and younger in the United States
Retrospective observational study based on a nationwide administrative database, aimed at describing contemporary trends in the use of TAVR, surgical bioprosthetic valves, and mechanical valves among patients aged 40 to 65 years undergoing isolated aortic valve replacement in the United States.
Combined heart-liver transplantation in failing Fontan circulation: between opportunity and optimal timing
This article analyzes the outcomes of combined heart-liver transplantation in patients with Fontan circulation treated at pediatric hospitals in the United States.
VA-ECMO after congenital heart surgery: when to initiate it and when to discontinue it?
Retrospective single-centre study analysing 23 years of experience at a German referral centre with the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as circulatory support following congenital heart surgery.
Are we reaching cardiac resynchronisation too late in patients with a systemic right ventricle?
The largest international cohort to date assessing the role of cardiac resynchronisation therapy in patients with a systemic right ventricle due to congenitally corrected transposition of the great arteries or TGA repaired with an atrial switch procedure.
TAVR vs isolated SAVR in low-risk patients: 5-year comparative outcomes from the Evolut Low Risk trial
Post hoc subanalysis of the Evolut Low Risk trial comparing 5-year outcomes in 1164 low-risk patients with severe aortic stenosis undergoing isolated aortic valve replacement, either transcatheter (TAVR) or surgical (SAVR).
