Low-dose anticoagulation in patients with On-X® aortic prosthesis: Increased safety without compromising efficacy

First results from a prospective, multicenter, single-arm registry clinical study aimed at evaluating the safety of low-dose warfarin anticoagulation combined with aspirin in patients undergoing isolated aortic valve replacement with the On-X® prosthesis (Artivion®) after 5 years of follow-up, comparing these results with the historical control group from the randomized PROACT clinical trial.