Should the left atrial appendage be closed during mitral repair in patients without atrial fibrillation?

This study analyzes a large US national registry to evaluate whether concomitant left atrial appendage (LAA) closure during isolated mitral valve repair in patients without atrial fibrillation (AF) is associated with better long-term outcomes, specifically thromboembolic events and mortality, comparing patients who underwent LAA closure with those who did not.